Epigenome data release: a participant-centered approach to privacy protection

 Dyke, Stephanie O.M., Cheung, W.A., Joly, Y., et al., “Epigenome data release: a participant-centered approach to privacy protection” 16:142 (2015) doi:10.1186/s13059-015-0723-0 Genome Biology 1-12.

Large-scale epigenome mapping by the NIH Roadmap Epigenomics Project, the ENCODE Consortium and the International Human Epigenome Consortium (IHEC) produces genome-wide DNA methylation data at one base-pair resolution. We examine how such data can be made open-access while balancing appropriate interpretation and genomic privacy. We propose guidelines for data release that both reduce ambiguity in the interpretation of open-access data and limit immediate access to genetic variation data that are made available through controlled access.

This content has been updated on January, 6 2016 at 15 h 45 min.